Improving Pediatric Sepsis Outcomes Change Package

This improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.

Published April 01, 2025|
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Every year, more than 3 million children worldwide die from sepsis, including 7,000 in the U.S.

From 2016-2023, 66 children’s hospitals across the U.S. came together to share data and collaborate on solutions to reduce deaths and complications due to sepsis. Eight years of learning and data from more than 100,000 sepsis cases culminated in a comprehensive resource for improving pediatric sepsis care.

Called a change package, this improvement toolkit equips hospitals with practical resources and evidence-based strategies proven to reduce pediatric deaths from sepsis.

What's in the change package?

  • A lifesaving bundle of care
  • Strategies for effective implementation
  • Key measures for tracking performance
  • 70+ sepsis tools from high-performing hospitals

Download the change package to learn more.

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